GADD45a Promoter Regulation by a Functional Genetic Variant Associated with Acute Lung Injury
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چکیده
منابع مشابه
GADD45a Promoter Regulation by a Functional Genetic Variant Associated with Acute Lung Injury
RATIONALE Growth arrest DNA damage inducible alpha (GADD45a) is a stress-induced gene we have shown to participate in the pathophysiology of ventilator-induced lung injury (VILI) via regulation of mechanical stress-induced Akt ubiquitination and phosphorylation. The regulation of GADD45a expression by mechanical stress and its relationship with acute lung injury (ALI) susceptibility and severit...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0100169